Natural deaths ending in the morgue: a statistical and investigative analysis in criminalistics and forensic sciences

Introduction. This research proposes a comprehensive analysis of deaths considered natural using the Forensic Information Management System (SIGIF) and the National System of Legal Medicine and Forensic Sciences (SNMLCF) in Zones 1 and 2 in the year 2024. The aim is to define the classification of cases that can be classified as violent according to the Comprehensive Organic Penal Code (COIP), thus providing valuable information to the wider community. With the aim of determining the classification of cases that could be reclassified as violent, as indicated by the Comprehensive Organic Criminal Code (COIP), thus providing valuable information for the community at large. Methodology. A quantitative and qualitative approach was used to analyze the 2024 database, identifying the reclassification rate and associated factors. The combination of methods provides clarity in addressing the research question, also considering the analytical method. Results. In this challenge, a qualitative, quantitative, and analytical analysis was conducted on the initial DINASED database, issued by SIGIF and SNMLC 2024. After a rigorous analysis, the results of this research, which records natural deaths admitted to the morgue due to numerous factors, were concluded to be important. These results are useful for organizing and strengthening the reclassification of forensic research, which allows for more effective and secure public policy design. Conclusion. There are underlying factors that justify forensic intervention, considering the COIP's focus on violent deaths. Therefore, reclassification is a key factor in the investigation. It allowed for the identification of risks of error and the formulation of recommendations to optimize the classification processes for natural deaths in the morgue. However, the lack of valid clinical documentation highlights the need to strengthen communication between health services and the Prosecutor's Office to optimize forensic management. General Area of Study: Health. Specific area of study: Forensic Sciences. Type of study: Original articles.

Dora Alicia López Chávez

6-21

Biomimetic remineralization of enamel and dentin: a review of the literature

Objective. To analyze the literature regarding enamel and dentin remineralization with biomimetic materials to understand their effectiveness and clinical applications. Methodology. Comprehensive research of scientific articles was conducted that included in vitro studies, systematic reviews, and meta-analyses published between 2019 and 2024. The databases consulted were Pubmed, Science Direct, and Springer Link and Google academic was used as a secondary search engine. Results. Despite all the promising studies, biomimetic strategies still face challenges in the field of dentistry. Conclusion. Biomimetic remineralization has evolved from an experimental concept to an emerging clinical reality, establishing P11-4 peptides, stabilized CPP-ACP dentifrices, and zinc-carbonate hydroxyapatite as viable therapeutic options for immediate implementation. The trend toward multifunctional materials combining remineralizing, antibacterial, and anti-adhesive properties represents a paradigmatic evolution that transcends traditional restorative approaches toward comprehensive tissue regeneration. Despite promising evidence, a critical gap persists between abundant laboratory research and limited clinical evidence requiring priority attention. Biomimetic remineralization possesses transformative potential to revolutionize preventive and therapeutic management of dental caries, transitioning toward a regenerative model that could significantly reduce the burden of oral disease at the population level. General Area of Study: Medicine. Specific area of study: Dentistry. Type of study: Systematic bibliographic review

Nancy Pilar Sauca Chalán, Yuliana Elizabeth Paladinez Carrión, Iván Andrés Palacios Astudillo

33-64

Therapeutics of genu valgum according to pediatric age: bibliographic review

Introduction: Genu valgum is a common orthopedic disorder in children that can affect their mobility and quality of life if not accurately diagnosed and treated. In Latin America, the lack of unified criteria and organized information makes its management difficult, especially in Ecuador, where there is no updated review of age-specific treatments. Given the growing concern about children's musculoskeletal health and the inequality in access to specialized care, it is essential to compile and analyze the available evidence to optimize diagnosis and treatment, improve clinical practice and patients' quality of life, and avoid unnecessary interventions. Objective: To analyze the scientific information available on the treatments used for genu valgum in the pediatric population, evaluating their efficacy according to the different ages, in research conducted in the last five years. Method: A theoretical review was conducted through the PICOT strategy: using DeCS/MeSH terms in relevant health databases such as PubMed, Scopus, Google Scholar, Web of Science and Springer Link. Specific search strategies will be applied using keywords and MeSH (Medical Subject Headings) terms to identify relevant primary studies such as “Genu valgum,” “Child,” “Treatment” accompanied by Boolean operators such as ‘AND’ and “OR.” Results: Its origins can be congenital, nutritional, biomechanical or postural. To evaluate it, measurements such as the thiofemoral angle, intermalleolar and intercondylar distances, and radiographs are used. Treatment varies from physiotherapy and corrective exercises to surgery in severe cases. The benefits of early therapeutic programs to improve posture and function are also highlighted. Furthermore, the psychosocial impact of genu valgum is highlighted, affecting the self-esteem and social interaction of the child or adolescent. Conclusions: genu valgum represents more than a physical alteration; it is an indication of the organism that suggests the need for clinical, preventive, and empathic intervention. This analysis helps to deepen the understanding of the situation and paves the way for new therapeutic options, adapted and focused on the well-being of the child being in continuous evolution. General Area of Study: Medicine. Specific area of study: Pediatric Traumatology and Orthopedics. Type of study: Bibliographic review.

Andrés Fernando Escobar Beltrán, Manuel Ricardo Valverde Gavilanes

65-87

Efficacy of triantibiotic paste in endodontics: antibacterial activity against resistant strains of Enterococcus faecalis. An exhaustive review

Introduction: Enterococcus faecalis is one of the main microorganisms associated with endodontic treatment failures due to its ability to form biofilms, survive in harsh conditions, and exhibit antimicrobial resistance, particularly to vancomycin. In response to this clinical challenge, the Triple Antibiotic Paste (TAP), composed of ciprofloxacin, metronidazole, and minocycline, has shown promising results due to its synergistic antibacterial activity against persistent bacteria in root canal systems. Objective: To evaluate the antibacterial efficacy of triple antibiotic, paste against resistant strains of Enterococcus faecalis through an exhaustive review. Methodology: An exhaustive review was conducted following the PRISMA guidelines. A total of 138 scientific articles were identified and analyzed from indexed databases (PubMed, Scopus, and ScienceDirect), using MeSH and DeCS descriptors combined with Boolean operators AND/OR. Results: Most included studies demonstrated that TAP exhibits high antimicrobial effectiveness against E. faecalis, including strains resistant to conventional antibiotics. Both in vitro and vivo investigations revealed a significant reduction in bacterial load and disruption of radicular biofilms, outperforming other intracanal medications such as calcium hydroxide and chlorhexidine. Conclusions: Triple antibiotic paste is an effective therapeutic option in regenerative endodontics and retreatment procedures, particularly in persistent infections caused by Enterococcus faecalis. Its rational and standardized use can improve clinical outcomes in complex cases, making it a relevant tool in managing antimicrobial resistance within the root canal system. General area of study: Health Sciences. Specific area: Dentistry. Study type: Literature review.

Elena Patricia Cevallos Fernández, Katherine de los Ángeles Cuenca León

88-104