Introduction. The resinous materials currently printed in Dentistry are becoming more popular in the field of prosthodontics, they contain organic and inorganic fillers nano and microhybrid ceramics including silanized zirconium; this allows them to have an elevated level of fracture and flexural resistance. Its elaboration is indirect in a 3D printer, after elaboration of an exocad design where plural fixed prostheses of up to 3 units, veneers, inlays can be planned. In this way, 3D composites offer an efficient and durable alternative for various applications in restorative dentistry. Objective. To evaluate and compare the roughness and shore D hardness of Prizma Bio-Crown 3D resin at different polymerization times. Methodology. Experimental in vitro, 100 evaluate samples of nano hybrid resin (Prizma bio crown) were performed. The samples were made with 3D printing (LCD) with dimensions of 12 mm high by 6 mm wide, each sample block was subjected to a polishing protocol that includes the use of silicone discs, goat hair and felt, accompanied by two polishing pastes: DURA Polishing and Superpolishing. Polishing was done for 20 seconds at each step, using an electric motor at different speeds (10,000 rpm, 5,000 rpm, and 4,000 rpm, respectively). Results. The study reveals a significant variability in roughness levels between the diverse groups of samples, indicating substantial variations in manufacturing, finishing and polishing conditions. Using a detailed measurement scale, we evaluated the average roughness (Ra) on four sides of the samples for each group, revealing distinctive patterns based on treatment time and the finishing and polishing technique employed. These results suggest that the optimization of these parameters is crucial to obtain restorations with high-quality Prizma Bio Crown resin, with smooth, aesthetic and wear-resistant surfaces. Conclusion. The processes of pre-printing, post-printing, polymerization time and polishing protocol were identified as determining factors in the physical properties of the material, especially in its roughness and Shore D hardness. These findings provide a guide to standardize these parameters and improve both aesthetics and functionality in the processing of 3D printed Bio Crown resin in the dental field. General area of study: Dentistry. Specific area of study: Oral Rehabilitation. Type of study: Original article.