Digital planning and 3D surgical guide in dental autotransplantation: a literature review
Main Article Content
Abstract
Introduction. Dental autotransplantation is a biologically predictable procedure when periodontal ligament vitality is preserved and extraoral exposure time is minimized. Digital planning, cone-beam computed tomography (CBCT), 3D surgical guides, and three-dimensional printing have improved the accuracy and predictability of this procedure. Objective. To analyze the application of a digital workflow using CBCT, intraoral scanning, and 3D-printed surgical guides in the planning and execution of dental autotransplantation, evaluating their contribution to surgical precision and periodontal tissue preservation. Methodology. An initial literature review on digitally assisted dental autotransplantation was conducted. Subsequently, four clinical cases planned to use a digital workflow are presented, that included CBCT, intraoral scanning, and 3D-printed surgical guides in patients aged 25, 28, 31, and 33 years. Results. All procedures showed extraoral exposure times of less than one-minute, functional stability, and no signs of root resorption or ankylosis during follow-up. Conclusion. The digital workflow applied to dental autotransplantation demonstrates high efficacy across different age groups and anatomical scenarios, enhancing surgical precision, preserving the periodontal ligament, and standardizing clinical protocols. General Area of Study: Dentistry. Specific area of study: Endodontics. Type of study: Case series with literature review.
Downloads
Download data is not yet available.
Article Details
How to Cite
Donoso Vega, J. D., & Rodriguez Reyes, F. G. (2026). Digital planning and 3D surgical guide in dental autotransplantation: a literature review. Anatomía Digital, 9(2), 74-93. https://doi.org/10.33262/anatomiadigital.v9i2.3671
Section
Articulos de revisión bibliográfica
References
1. González-Quintanilla D, Zamorano JP, Mella E, Pinto N, Brisso J, Rodriguez N, et al. Autotrasplante dental utilizando simulación virtual y un prototipo de modelo de impresión 3D. International Journal of Odontostomatology [Internet]. 2021 [citado 13 Ene 2026];15(1):271–277. Disponible en: https://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2021000100271&lng=en&nrm=iso&tlng=en
2. Criado Villalón P, Fernández González V, Medina del Valle J, Sáez-Torres IC. Autotrasplante dentario múltiple con planificación y modelos 3D. Revista Española de Cirugía Oral y Maxilofacial [Internet] 2024 [citado 13 Ene 2026];46(2):99–103. Disponible en: https://www.revistacirugiaoralymaxilofacial.es/autotrasplante-dentario-multiple-con-planificacion-y-modelos-3d898
3. Srivastava S, Gupta K, Dubey S, Singh A. Guided autotransplantation of tooth. National Journal of Maxillofacial Surgery [Internet]. 2022 [cited 13 Jan 2026];13(Suppl 1):S136-9. Available from: https://pubmed.ncbi.nlm.nih.gov/36393944/
4. Babiuc I, Diaconeasa MȘ, Perieanu VȘ, Malița MA, Beuran IA, Burlibașa M. Case report: digitally driven tooth autotransplantation using surgical templates and three-dimensional printed donor tooth replica. Frontiers in Oral Health [Internet]. 2025 Mar 19 [cited 13 Jan 2026];6:1537468. Available from: https://www.frontiersin.org/articles/10.3389/froh.2025.1537468
5. Riolobos Gonzalez MF, García Moreno S, López-Malla MJ. Autotrasplante dental inmediato guiado mediante simulación virtual y prototipo 3D. Científica dental: Revista científica de formación continuada. Científica Dental [Internet]. 2024 [citado 13 Ene 2026];21(2):100-105. Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=10081397
6. Borie E, Oliví DG, Orsi IA, Garlet K, Weber B, Beltrán V, et al. Platelet-rich fibrin application in dentistry: a literature review. International Journal of Clinical and Experimental Medicine [Internet]. 2015 [cited 13 Jan 2026];8(5):7922-7929. Available from: https://pubmed.ncbi.nlm.nih.gov/26221349/
7. Xu HD, Miron RJ, Zhang XX, Zhang YF. Allogenic tooth transplantation using 3D printing: a case report and review of the literature. World Journal of Clinical Cases [Internet]. 2019 [cited 13 Jan 2026];7(17):2587-2596. Available from: https://www.wjgnet.com/2307-8960/full/v7/i17/2587.htm
8. Pop SI, Bud E, Jánosi KM, Bud A, Kerekes-Máthé B. Three-dimensional surgical guides in orthodontics: the present and the future. Dental Journal (Basel) [Internet]. 2025 [cited 13 Jan 2026];13(2):74. Available from: https://pubmed.ncbi.nlm.nih.gov/39996948/
9. He W, Tian K, Xie X, Wang E, Cui N. Computer-aided autotransplantation of teeth with 3D printed surgical guides and arch bar: a preliminary experience PeerJ [Internet]. 2018 Nov 22 [cited 13 Jan 2026];6:e5939. Available from: https://peerj.com/articles/5939/
10. Elbana L, Rahimi H, Mohammadi M, Saeedi N, Ahmadyar R, Rezaee N, et al. Integration of digital technologies in implant dentistry: workflow, challenges, and opportunities. European Journal of Dental and Oral Health [Internet]. 2026 [cited 13 Jan 2026];7(1):22-28. Available from: https://www.eu-opensci.org/index.php/ejdent/article/view/13414
11. Yi K, Li Q, Lian X, Wang Y, Tang Z. Utilizing 3D bioprinted platelet-rich fibrin-based materials to promote the regeneration of oral soft tissue. Regenerative Biomaterials [Internet]. 2022 [cited 13 Jan 2026];9:rbac021. Available from: https://pubmed.ncbi.nlm.nih.gov/35558097/
12. Hijazi AH, Al-Hamed FS, Tamimi F, Al-Maweri SA, Hamdan N, Psutka DJ, et al. Regenerative potential of platelet concentrates in chronic oral mucosal lesions. Journal of Oral Biology and Craniofacial Research [Internet]. 2024 [cited 13 Jan 2026];14(2):216-221. Available from: https://pubmed.ncbi.nlm.nih.gov/38487393/
13. Kim MJ, Jeong JY, Ryu J, Jung S, Park HJ, Oh HK, et al. Accuracy of digital surgical guides for dental implants. Maxillofacial Plastic and Reconstructive Surgery [Internet]. 2022 Oct 25 [cited 13 Jan 2026];44(1):35. Available from: https://pubmed.ncbi.nlm.nih.gov/36282400/
14. Pedrinaci I, Calatrava J, Couso-Queiruga E, Bethencourt J del R, Sanz-Sanchez I, Gallucci GO, et al. Tooth autotransplantation with adjunctive application of enamel matrix derivatives using a digital workflow: a prospective case series. Journal of Dentistry [Internet]. 2024 [cited 13 Jan 2026];148:105131. Available from: https://pubmed.ncbi.nlm.nih.gov/38950765/
15. Abella F, Roig M. Tooth autotransplantation: a proven therapeutic option. American Association of Endodontists [Internet]. 2020 [cited 13 Jan 2026]. Available from: https://www.aae.org/specialty/tooth-autotransplantation-a-proven-therapeutic-option/
16. Alattas MH. The role of 3D printing in endodontic treatment planning: a comprehensive review. European Journal of Dentistry [Internet]. 2025 May [cited 13 Jan 2026];19(2):298-304. Available from: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0044-1791242
17. Dioguardi M, Guerra C, Laterza P, Illuzzi G, Sovereto D, Laneve E, et al. Mapping review of the correlations between periodontitis, dental caries, and endocarditis. Dental Journal (Basel) [Internet]. 2025 [cited 13 Jan 2026];13(5):215. Available from: https://www.mdpi.com/2304-6767/13/5/215
18. Van der Meer W. 3D workflows in orthodontics, maxillofacial surgery and prosthodontics [Thesis doctoral from Internet, University Medical Center Groningen, Groningen]. 2016 [cited 13 Jan 2026]. Available from: https://pure.rug.nl/ws/portalfiles/portal/35539918/Chapter_10_.pdf
19. Cousley RRJ, Gibbons A, Nayler J. A 3D printed surgical analogue to reduce donor tooth trauma during autotransplantation. Journal of Orthodontics [Internet]. 2017 [cited 13 Jan 2026];44(4):287-293. Available from: https://www.tandfonline.com/doi/full/10.1080/14653125.2017.1371960
20. Anssari Moin D, Verweij JP, Waars H, van Merkesteyn R, Wismeijer D. Accuracy of computer-assisted template-guided autotransplantation of teeth with custom three-dimensional designed/printed surgical tooling: a cadaveric study. Journal of Oral and Maxillofacial Surgery [Internet]. 2017 [cited 13 Jan 2026];75(5):925.e1-925.e7. Available from: https://pubmed.ncbi.nlm.nih.gov/28157492/
21. Rugani P, Brcic I, Magyar M, Schwarze UY, Jakse N, Ebeleseder K. Pulp Revascularization in an Autotransplanted Mature Tooth: Visualization with Magnetic Resonance Imaging and Histopathologic Correlation. Journal of Clinical Medicine [Internet]. 2023 [cited 13 Jan 2026];12(18):6008. Available from: https://pubmed.ncbi.nlm.nih.gov/37762947/
22. Dhillon IK, Khor MM, Tan BL, Wong Wen RC, Duggal MS, Soh SH, et al. Tooth autotransplantation with 3D‐printed replicas as part of interdisciplinary management of children and adolescents: Two case reports. Dental Traumatology [Internet]. 2023 Sep [cited 13 Jan 2026];39(Suppl 1):81-9. Available from: https://onlinelibrary.wiley.com/doi/10.1111/edt.12837
23. Valverde Haro HP, Erazo Conde AD. Case Report: Dental autotransplantation for the resolution of odontogenic sinusitis using 3D replication. Frontiers in Dental Medicine [Internet]. 2025 [cited 13 Jan 2026];6:1607035. Available from: https://www.frontiersin.org/articles/10.3389/fdmed.2025.1607035
24. Alfertshofer M, Gebhart F, Nolte D. Template-guided autogenous tooth transplantation using a CAD/CAM dental replica in a complex anatomical scenario: a case report. Dental Journal (Basel) [Internet]. 2025 [cited 13 Jan 2026];13(7):281. Available from: https://pubmed.ncbi.nlm.nih.gov/40710126/
25. Walch B, Gaggl A, Zeman-Kuhnert K, Brandtner C. Autotransplantation of impacted third molars to DCIA free flap in adolescent patient: a case report. Children (Basel) [Internet]. 2025 [cited 13 Jan 2026];12(3):370. Available from: https://pubmed.ncbi.nlm.nih.gov/40150652/
26. Cuesta Román R, López-González ÁA, Obrador de Hevia J, Arroyo Bote S, Paublini Oliveira H, Riutord-Sbert P. Digitally guided modified intentional replantation for a tooth with hopeless periodontal prognosis: a case report. Diagnostics (Basel) [Internet]. 2025 [cited 13 Jan 2026];15(23):3080. Available from: https://www.mdpi.com/2075-4418/15/23/3080
27. Bi C, Zhang W, Peng B. Autotransplantation of a third molar to replace compromised molar with the individual three‐dimensional printed ultrasonic osteotome: a case report. Case Reports in Dentistry [Internet]. 2025 [cited 13 Jan 2026];2025:6146337. Available from: https://pubmed.ncbi.nlm.nih.gov/39872409/
28. González Guachizaca GV, Morocho Morocho NP, Lugo Pinto MA, Rodriguez Reyes FG. Endodontic regeneration with A-PRF and I-PRF in a permanent tooth with immature apex: a clinical case report. Anatomía Digital [Internet]. 2025Nov.13 [cited 2026Jan13];8(4):57-3. Available from: https://doi.org/10.33262/anatomiadigital.v8i4.3558
29. Cherres Quiroz JA, Rodriguez Reyes FG. Intentional replantation with I-PRF for periapical healing. Anatomía Digital [Internet]. 2026Jan.5 [cited 2026Jan13];9(1):82-5. Available from: https://doi.org/10.33262/anatomiadigital.v9i1.3577
30 Flores Sacoto ML, Duran Neira PA, Bastidas Calva MZ, Álvarez Álvarez DP. Dental innovation: a 3D printing of canine teeth to improve endodontic training. Anatomía Digital [Internet]. 2024Aug.26 [cited 2026Jan13];7(3):120-36. Available from: https://doi.org/10.33262/anatomiadigital.v7i3.3150
31. Martínez Vergara JV, Monar Naranjo MB, Heredia Gamboa EA, García Analuisa DP. From concept to reality: integrated design methodology using sketches, renderings, technical drawings, and 3D printing. Conciencia Digital [Internet]. 2024Dec.27 [cited 2026Jan13];7(4.1):85-102. Available from: https://doi.org/10.33262/concienciadigital.v7i4.1.3304
2. Criado Villalón P, Fernández González V, Medina del Valle J, Sáez-Torres IC. Autotrasplante dentario múltiple con planificación y modelos 3D. Revista Española de Cirugía Oral y Maxilofacial [Internet] 2024 [citado 13 Ene 2026];46(2):99–103. Disponible en: https://www.revistacirugiaoralymaxilofacial.es/autotrasplante-dentario-multiple-con-planificacion-y-modelos-3d898
3. Srivastava S, Gupta K, Dubey S, Singh A. Guided autotransplantation of tooth. National Journal of Maxillofacial Surgery [Internet]. 2022 [cited 13 Jan 2026];13(Suppl 1):S136-9. Available from: https://pubmed.ncbi.nlm.nih.gov/36393944/
4. Babiuc I, Diaconeasa MȘ, Perieanu VȘ, Malița MA, Beuran IA, Burlibașa M. Case report: digitally driven tooth autotransplantation using surgical templates and three-dimensional printed donor tooth replica. Frontiers in Oral Health [Internet]. 2025 Mar 19 [cited 13 Jan 2026];6:1537468. Available from: https://www.frontiersin.org/articles/10.3389/froh.2025.1537468
5. Riolobos Gonzalez MF, García Moreno S, López-Malla MJ. Autotrasplante dental inmediato guiado mediante simulación virtual y prototipo 3D. Científica dental: Revista científica de formación continuada. Científica Dental [Internet]. 2024 [citado 13 Ene 2026];21(2):100-105. Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=10081397
6. Borie E, Oliví DG, Orsi IA, Garlet K, Weber B, Beltrán V, et al. Platelet-rich fibrin application in dentistry: a literature review. International Journal of Clinical and Experimental Medicine [Internet]. 2015 [cited 13 Jan 2026];8(5):7922-7929. Available from: https://pubmed.ncbi.nlm.nih.gov/26221349/
7. Xu HD, Miron RJ, Zhang XX, Zhang YF. Allogenic tooth transplantation using 3D printing: a case report and review of the literature. World Journal of Clinical Cases [Internet]. 2019 [cited 13 Jan 2026];7(17):2587-2596. Available from: https://www.wjgnet.com/2307-8960/full/v7/i17/2587.htm
8. Pop SI, Bud E, Jánosi KM, Bud A, Kerekes-Máthé B. Three-dimensional surgical guides in orthodontics: the present and the future. Dental Journal (Basel) [Internet]. 2025 [cited 13 Jan 2026];13(2):74. Available from: https://pubmed.ncbi.nlm.nih.gov/39996948/
9. He W, Tian K, Xie X, Wang E, Cui N. Computer-aided autotransplantation of teeth with 3D printed surgical guides and arch bar: a preliminary experience PeerJ [Internet]. 2018 Nov 22 [cited 13 Jan 2026];6:e5939. Available from: https://peerj.com/articles/5939/
10. Elbana L, Rahimi H, Mohammadi M, Saeedi N, Ahmadyar R, Rezaee N, et al. Integration of digital technologies in implant dentistry: workflow, challenges, and opportunities. European Journal of Dental and Oral Health [Internet]. 2026 [cited 13 Jan 2026];7(1):22-28. Available from: https://www.eu-opensci.org/index.php/ejdent/article/view/13414
11. Yi K, Li Q, Lian X, Wang Y, Tang Z. Utilizing 3D bioprinted platelet-rich fibrin-based materials to promote the regeneration of oral soft tissue. Regenerative Biomaterials [Internet]. 2022 [cited 13 Jan 2026];9:rbac021. Available from: https://pubmed.ncbi.nlm.nih.gov/35558097/
12. Hijazi AH, Al-Hamed FS, Tamimi F, Al-Maweri SA, Hamdan N, Psutka DJ, et al. Regenerative potential of platelet concentrates in chronic oral mucosal lesions. Journal of Oral Biology and Craniofacial Research [Internet]. 2024 [cited 13 Jan 2026];14(2):216-221. Available from: https://pubmed.ncbi.nlm.nih.gov/38487393/
13. Kim MJ, Jeong JY, Ryu J, Jung S, Park HJ, Oh HK, et al. Accuracy of digital surgical guides for dental implants. Maxillofacial Plastic and Reconstructive Surgery [Internet]. 2022 Oct 25 [cited 13 Jan 2026];44(1):35. Available from: https://pubmed.ncbi.nlm.nih.gov/36282400/
14. Pedrinaci I, Calatrava J, Couso-Queiruga E, Bethencourt J del R, Sanz-Sanchez I, Gallucci GO, et al. Tooth autotransplantation with adjunctive application of enamel matrix derivatives using a digital workflow: a prospective case series. Journal of Dentistry [Internet]. 2024 [cited 13 Jan 2026];148:105131. Available from: https://pubmed.ncbi.nlm.nih.gov/38950765/
15. Abella F, Roig M. Tooth autotransplantation: a proven therapeutic option. American Association of Endodontists [Internet]. 2020 [cited 13 Jan 2026]. Available from: https://www.aae.org/specialty/tooth-autotransplantation-a-proven-therapeutic-option/
16. Alattas MH. The role of 3D printing in endodontic treatment planning: a comprehensive review. European Journal of Dentistry [Internet]. 2025 May [cited 13 Jan 2026];19(2):298-304. Available from: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0044-1791242
17. Dioguardi M, Guerra C, Laterza P, Illuzzi G, Sovereto D, Laneve E, et al. Mapping review of the correlations between periodontitis, dental caries, and endocarditis. Dental Journal (Basel) [Internet]. 2025 [cited 13 Jan 2026];13(5):215. Available from: https://www.mdpi.com/2304-6767/13/5/215
18. Van der Meer W. 3D workflows in orthodontics, maxillofacial surgery and prosthodontics [Thesis doctoral from Internet, University Medical Center Groningen, Groningen]. 2016 [cited 13 Jan 2026]. Available from: https://pure.rug.nl/ws/portalfiles/portal/35539918/Chapter_10_.pdf
19. Cousley RRJ, Gibbons A, Nayler J. A 3D printed surgical analogue to reduce donor tooth trauma during autotransplantation. Journal of Orthodontics [Internet]. 2017 [cited 13 Jan 2026];44(4):287-293. Available from: https://www.tandfonline.com/doi/full/10.1080/14653125.2017.1371960
20. Anssari Moin D, Verweij JP, Waars H, van Merkesteyn R, Wismeijer D. Accuracy of computer-assisted template-guided autotransplantation of teeth with custom three-dimensional designed/printed surgical tooling: a cadaveric study. Journal of Oral and Maxillofacial Surgery [Internet]. 2017 [cited 13 Jan 2026];75(5):925.e1-925.e7. Available from: https://pubmed.ncbi.nlm.nih.gov/28157492/
21. Rugani P, Brcic I, Magyar M, Schwarze UY, Jakse N, Ebeleseder K. Pulp Revascularization in an Autotransplanted Mature Tooth: Visualization with Magnetic Resonance Imaging and Histopathologic Correlation. Journal of Clinical Medicine [Internet]. 2023 [cited 13 Jan 2026];12(18):6008. Available from: https://pubmed.ncbi.nlm.nih.gov/37762947/
22. Dhillon IK, Khor MM, Tan BL, Wong Wen RC, Duggal MS, Soh SH, et al. Tooth autotransplantation with 3D‐printed replicas as part of interdisciplinary management of children and adolescents: Two case reports. Dental Traumatology [Internet]. 2023 Sep [cited 13 Jan 2026];39(Suppl 1):81-9. Available from: https://onlinelibrary.wiley.com/doi/10.1111/edt.12837
23. Valverde Haro HP, Erazo Conde AD. Case Report: Dental autotransplantation for the resolution of odontogenic sinusitis using 3D replication. Frontiers in Dental Medicine [Internet]. 2025 [cited 13 Jan 2026];6:1607035. Available from: https://www.frontiersin.org/articles/10.3389/fdmed.2025.1607035
24. Alfertshofer M, Gebhart F, Nolte D. Template-guided autogenous tooth transplantation using a CAD/CAM dental replica in a complex anatomical scenario: a case report. Dental Journal (Basel) [Internet]. 2025 [cited 13 Jan 2026];13(7):281. Available from: https://pubmed.ncbi.nlm.nih.gov/40710126/
25. Walch B, Gaggl A, Zeman-Kuhnert K, Brandtner C. Autotransplantation of impacted third molars to DCIA free flap in adolescent patient: a case report. Children (Basel) [Internet]. 2025 [cited 13 Jan 2026];12(3):370. Available from: https://pubmed.ncbi.nlm.nih.gov/40150652/
26. Cuesta Román R, López-González ÁA, Obrador de Hevia J, Arroyo Bote S, Paublini Oliveira H, Riutord-Sbert P. Digitally guided modified intentional replantation for a tooth with hopeless periodontal prognosis: a case report. Diagnostics (Basel) [Internet]. 2025 [cited 13 Jan 2026];15(23):3080. Available from: https://www.mdpi.com/2075-4418/15/23/3080
27. Bi C, Zhang W, Peng B. Autotransplantation of a third molar to replace compromised molar with the individual three‐dimensional printed ultrasonic osteotome: a case report. Case Reports in Dentistry [Internet]. 2025 [cited 13 Jan 2026];2025:6146337. Available from: https://pubmed.ncbi.nlm.nih.gov/39872409/
28. González Guachizaca GV, Morocho Morocho NP, Lugo Pinto MA, Rodriguez Reyes FG. Endodontic regeneration with A-PRF and I-PRF in a permanent tooth with immature apex: a clinical case report. Anatomía Digital [Internet]. 2025Nov.13 [cited 2026Jan13];8(4):57-3. Available from: https://doi.org/10.33262/anatomiadigital.v8i4.3558
29. Cherres Quiroz JA, Rodriguez Reyes FG. Intentional replantation with I-PRF for periapical healing. Anatomía Digital [Internet]. 2026Jan.5 [cited 2026Jan13];9(1):82-5. Available from: https://doi.org/10.33262/anatomiadigital.v9i1.3577
30 Flores Sacoto ML, Duran Neira PA, Bastidas Calva MZ, Álvarez Álvarez DP. Dental innovation: a 3D printing of canine teeth to improve endodontic training. Anatomía Digital [Internet]. 2024Aug.26 [cited 2026Jan13];7(3):120-36. Available from: https://doi.org/10.33262/anatomiadigital.v7i3.3150
31. Martínez Vergara JV, Monar Naranjo MB, Heredia Gamboa EA, García Analuisa DP. From concept to reality: integrated design methodology using sketches, renderings, technical drawings, and 3D printing. Conciencia Digital [Internet]. 2024Dec.27 [cited 2026Jan13];7(4.1):85-102. Available from: https://doi.org/10.33262/concienciadigital.v7i4.1.3304