Effectiveness of cluster of cuadrupe differentiation (CD4) in forecast of patients with HIV.

Main Article Content

Laura Judith Zúñiga Fariño
Lorena Paola Ramírez Morán
Pedro José Orellana Fariño
Nancy Corina Sánchez Coronel

Abstract

Introduction. The human immunodeficiency virus (HIV) is one that destroys certain cells of the immune system, altering or canceling its function. A CD4 count below 200 cells / mm3 indicates serious damage to the immune system, it is a sign of AIDS in people infected with HIV, considered a public health problem, both because of the impressive morbidity and mortality figures. Objective. To determine the efficacy of Cluster of quadrupe differentiation (CD4) in prognosis of patients with HIV from Teodoro Maldonado Carbo Hospital of the year 2018. Methodology. The research design was quantitative, retrospective, descriptive and transversal. The population was 543 cases and the sample of 100 patients taken from the medical records of the AS400 system of 2018, a data collection sheet was made that consisted of 13 items, was validated by judgments of specialists and health experts qualifying validity, relevance and coherence. Results. Among the most frequent results, 57% met the prognosis in the effectiveness of CD4, male (81%), 25 to 35 years old (30%), Mestizos (81%), from the province of Guayas (85%), active type affiliation (71%), presented complications (73%), tuberculosis (34%), the initial value of CD4 at 3 months was in patients between 200 and 500 cells / mm3 with (51%) , value at 6 months was greater than 500 cells / mm3 with (52%). Conclusion. It was concluded that more than half have CD4 efficacy, however many patients presented complications during treatment.

Downloads

Download data is not yet available.

Article Details

How to Cite
Zúñiga Fariño, L. J., Ramírez Morán, L. P., Orellana Fariño, P. J., & Sánchez Coronel, N. C. (2020). Effectiveness of cluster of cuadrupe differentiation (CD4) in forecast of patients with HIV. ConcienciaDigital, 3(2.2), 6-18. https://doi.org/10.33262/concienciadigital.v3i2.2.1242
Section
Artículos

References

Boza Cordero, R. (2016). Orígenes del VIH/SIDA. Revista Clínica de la Escuela de Medicina UCR – HSJD, 6(4), 48-60. Obtenido de https://www.medigraphic.com/pdfs/revcliescmed/ucr-2016/ucr164g.pdf
Buzon, M., Martin-Gayo, E., Pereyra, F., Ouyang, Z., Sun, H., Li, J., & Lichterfeld, M. (2014). Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells. J Virol, 88(17), 10056-10065. Obtenido de https://www.ncbi.nlm.nih.gov/pubmed/24965451
Cabo, R. M., Losa García, J. E., Iglesias Franco, H., & Iglesias González. (2014). Promoción de la detección del virus de la inmunodeficiencia humana en atención primaria. Gaceta Sanitaria, 26(2), 116–122. Obtenido de http://scielo.isciii.es/pdf/gs/v26n2/original2.pdf
Cabrera Alonso, S. G., Arteta Dalchiele, Z., Meré Rouco, J. J., & Cavalleri Ferrari, F. (2018). Calidad de vida relacionada a la salud en personas con VIH y factores asociados. Revista Médica Uruguay, 34(1), 7-19. Obtenido de scielo.edu.uy/pdf/rmu/v34n1/1688-0390-rmu-34-01-00003.pdf
Caja Calvo, A., Rocher Milla, J., Flores Cid, E., Soler Company, J. E., & Peris Ribera. (2015). Supervivencia de las mujeres infectadas por el VIH tras la aparición del TARGA. Anales de Medicina Interna, 24(10). Obtenido de http://scielo.isciii.es/pdf/ami/v24n10/original4.pdf
Chow, W., Lim, S., Ong, L., Yong, Y., Takebe, Y., Kamarulzaman, A., & Tee, K. (2015). Impact of HIV-1 Subtype on the Time to CD4+ T-Cell Recovery in Combination Antiretroviral Therapy (cART)-Experienced Patients. PLoS ONE, 10(9), 0137281.
Costagliola, D., Lacombe, J., Ghosn, J., & et al. (2014). CD4+ cell count recovery in naive patients initiating ART, who achieved and maintained plasma HIV-RNA suppression. J Int AIDS Soc, 17(4 suppl 3), 19481.
Guerrero Lara, A. J. (2016). Trends over calendar time in antiretroviral treatment success and failure in HIV clinic populations. HIV Med, 11, 432-8.
Lanoy, E., May, M., Mocroft, A., & et al. (2009). Prognosis of patients treated with ART from 36 months after initiation, according to current and previous CD4 cell count and plasma HIV-1 RNA measurements. AIDS, 23, 2199-208.
May, M., Ingle, S., Costagliola, D., Justice, A., de Wolf, F., & Cavassini, M. (2014). Cohort profile: Antiretroviral Therapy Cohort Collaboration (ART-CC). Int J Epidemiol, 43, 691-702.
McNairy, M., & El-Sadr, W. (2014). Antiretroviral therapy for the prevention of HIV transmission: what will it take? Clin. Infect. Dis., 1003-1011.
Noda Albelo, A. L., Vidal Tallet, L. A., Pérez Lastre, J. E., & Cañete Villafranca, R. (2014). Interpretación clínica del conteo de linfocitos T CD4 positivos en la infección por VIH. Revista Cubana de Medicina, 52(2), 118-127. Obtenido de http://scielo.sld.cu/pdf/med/v52n2/med05213.pdf
ONUSIDA. (2008). Informe sobre la epidemia Mundial del Sida. Programa Conjunto de las Naciones Unidas sobre el VIH/sida. México: Catalogación por la Biblioteca de la OMS. Obtenido de http://data.unaids.org/pub/globalreport/2008/jc1510_2008globalreport_es.pdf
Organización Mundial de Salud. (4 de Septiembre de 2019). VIH/Sida. Obtenido de Estrategia mundial del sector de la salud contra el VIH, 2016-2021: https://www.who.int/es/news-room/fact-sheets/detail/hiv-aids
Pacífico, J., & Gutiérrez, C. (2015). Información sobre la medicación y adherencia al tratamiento antirretroviral de gran actividad en pacientes con VIH/Sida de un Hospital de Lima, Perú. Rev. Peru Med Exp Salud Pública, 32(1), 66-72. Obtenido de http://www.scielo.org.pe/pdf/rins/v32n1/a10v32n1.pdf
Rodríguez Alfaro, M., Gross Fernández, C., & Casas Gross, S. (2016). Efectividad del tratamiento antirretroviral en pacientes con virus de inmunodeficiencia humana/sida en un hospital de Zimbabwe. Revista MEDISAN, 15(4), 433-441. Obtenido de http://scielo.sld.cu/pdf/san/v15n4/san05411.pdf
Varela Arévalo, M. T., & Hoyos Hernández, P. A. (2015). La adherencia al tratamiento para el VIH/SIDA: más allá de la toma de antirretrovirales. Revista de Salud Pública, 17(4), 528-540. Obtenido de https://www.scielosp.org/pdf/rsap/2015.v17n4/528-540/es