Risk factors and disorders due to folate deficiency in pregnant women

Main Article Content

Rosa María Zambrano Garcés
Sara Carolina Montaño Pérez
Alexandra Nathaly Lema Puin
Franklin Agustin Ruiz Quito

Abstract

Introduction: Folate deficiency is a health problem that can have significant consequences, especially during pregnancy. Folic acid, a synthetic form of folate, is crucial for cell development and the formation of the fetal nervous system. The shortage of this B vitamin in pregnant women is a major concern in maternal and child health, as it has been associated with serious complications. Objective: Determine the risk factors and disorders due to folate deficiency in pregnant women. Methodology: The development of this study is based on a type of descriptive research that allows analyzing the detailed variables in the theme or main idea. The research carried out has a qualitative approach that is based on the analysis of risk factors for folate deficiency in pregnant women. The descriptive study is based on the analysis of the established variables and analyzing the correlation between both. Results: The critical importance of folate during pregnancy and the harmful consequences that arise from its deficiency. The relationship between a lack of folate and neural tube defects is a central point, since this vitamin is essential for the correct formation of the neural tube in the fetus. Conclusion: Crucial factors that affect folate deficiency during pregnancy were identified, such as inadequate intake of foods rich in folate, clinical conditions such as celiac disease or intestinal diseases, excessive alcohol consumption, and a history of pregnancies with defects. of the neural tube.

Downloads

Download data is not yet available.

Article Details

How to Cite
Zambrano Garcés, R. M., Montaño Pérez, S. C., Lema Puin, A. N., & Ruiz Quito, F. A. (2024). Risk factors and disorders due to folate deficiency in pregnant women. ConcienciaDigital, 7(1.1), 68-85. https://doi.org/10.33262/concienciadigital.v7i1.1.2892
Section
Artículos

References

Barbosa, M., Barros, M., & Menezes, I. (2022). Suplementación con ácido fólico en el embarazo relacionada con el desarrollo de trastornos neurologicos de la infancia. Revista Investigación, Sociedad y Desarrollo, 11(6), 1-9. Obtenido de http://dx.doi.org/10.33448/rsd-v11i6.28746
Cañarte, M., & Castro, J. (2022). Anemia por déficit de nutrientes en mujeres de edad fértil: un enfoque sobre las características socioeconómicas, factores de riesgos, prevalencia. Revista FIPCAEC, 7(4), 1773-1797. Obtenido de https://fipcaec.com/index.php/fipcaec/article/view/708
Duarte, T. (2019). El ácido fólico diario puede reducir la diabetes gestacional. Eunive Kennedy Shriver National Institute, 2(3), 1-7. Obtenido de https://espanol.nichd.nih.gov/noticias/prensa/042919-folato
Hernández, F., Martínez, G., Rodríguez, Y., & Suárez, D. (2019). ácido fólico y el embarazo, como riesgo o beneficio. Revista Scielo Médica Electrónica, 41(1), 142-156. Obtenido de http://scielo.sld.cu/pdf/rme/v41n1/1684-1824-rme-41-01-142.pdf
Martínez, L., Jaramillo, L., & Villegas, J. (2018). Physiological Anemia versus Pathological Anemia in Pregnancy. Revista Cubana de Obstetricia y Ginecología, 44(2), 13-28. Obtenido de https://revginecobstetricia.sld.cu/index.php/gin/article/view/356/287
Miraglia, N., & Dehay, E. (2022). Folate Supplementation in Fertility and Pregnancy: The Advantages of (6S)5-Methyltetrahydrofolate. Revista Pub Med, 28(4), 12-17. Obtenido de https://pubmed.ncbi.nlm.nih.gov/35653630/
Montoro, M., Piedrafita, S., & Cañamares, P. (2021). Iron Deficiency in Celiac Disease: Prevalence, Health Impact, and Clinical Management. Revista PubMed, 28(13), 34-37. doi:10.3390/nu13103437
Na, L., Bai, Q., & Xiumei, Z. (2020). Research into the intervention effect of folic acid on arsenic-induced heart abnormalities in fetal rats during the periconception period. Revista BMC Cardiovasc. Disord., 20(1), 139-147. doi:10.1186/s12872-020-01418-z
Olapeju, B., Saifuddin, A., & Wang, G. (2019). Maternal postpartum plasma folate status and preterm birth in a high-risk US population. Revista PubMed, 22(7), 1281-1291. doi:10.1017/S1368980018003221
Perichart, O., Rodríguez, A., & Gutiérrez, P. (2021). Relevance of nutritional supplements during pregnancy: Role of iron, folic acid, vitamin D, calcium and multiple micronutrients. Revista Scielo Gaceta Médica de México, 156(3), 1-9. doi:https://doi.org/10.24875/gmm.m20000434
Qu, Y., Lin, S., & Zhuang, J. (2020). First-Trimester Maternal Folic Acid Supplementation Reduced Risks of Severe and Most Congenital Heart Diseases in Offspring: A Large Case-Control Study. Revista PubMed, 7(9), 1-24. doi:10.1161/JAHA.119.015652
Rodríguez, C., & Fresno, M. (2021). La correcta alimentación durante el embarazo. Revista Sanitaria de Investigación, 1(8), 1-11. Obtenido de https://revistasanitariadeinvestigacion.com/la-correcta-alimentacion-durante-el-embarazo-articulo-monografico/
Sagir, D., & Kuruoglu, E. (2020). Los efectos del ácido fólico y el topiramato sobre la regeneración de los nervios periféricos. Revista Histoquímica Biotecnología, 95(2), 105-112. doi:10.1080/10520295.2019.1637022
Talha, T., Karadas, H., & Akyildiz, I. (2019). Efecto del ácido fólico sobre la ototoxicidad inducida por cisplatino: un estudio funcional y morfológico. Revista Pub Med, 15(2), 237-246. doi:10.5152/iao.2019.6208
Tefera, A., Seifu, D., & Menon, M. (2022). Red blood cell folate level and associated factors of folate insufficiency among pregnant women attending antenatal care during their first trimester of pregnancy in Addis Ababa, Ethiopia. Revista Sage Open Med., 22(10), 22-29. doi:10.1177/20503121221118987
Tsiklauri, R., Jijeishvili, L., & Kherkheulidze. (2020). Neural tube defects and micronutients deficiency prevalence in Georgia. Revista Georgian Med News, 298(1), 61-66. Obtenido de https://pubmed.ncbi.nlm.nih.gov/32141851/
Wegmuller, R., Bentil, H., & Wirth, J. (2020). Anemia, micronutrient deficiencies, malaria, hemoglobinopathies and malnutrition in young children and non-pregnant women in Ghana: Findings from a national survey. Revista Plos One-PubMed, 15(1), 1-34. doi:10.1371/journal.pone.0228258
Yaremco, E., Inglis, A., & Hippman, C. (2018). Niveles de folato en glóbulos rojos en mujeres embarazadas con antecedentes de trastornos del estado de ánimo. Revista Birth Defects Res A Clin Mol Teratol, 97(6), 416-20. doi:10.1002/bdra.23144.
Zhang, Y., Kato, H., & Sato, H. (2019). Activación mitocondrial mediada por ácido fólico para la protección contra el estrés oxidativo en células madre de pulpa dental humana derivadas de dientes deciduos. Revista Bichem Biophys Res, 508(3), 850-856. doi:10.1016/j.bbrc.2018.11.169